Meet our Faculty Prof. Ruth Gallily

Prof. Ruth Gallily

The Hebrew University of Jerusalem, Israel
Ruth Gallily, cann10, agro tech

External Academic Positions and Awards:
Research Assoc.: Johns Hopkins Univ., 1962-64;
Weizmann Inst., 1964-67;
Research Fellow, Calif. Inst. of Tech 1967-69.
Visiting Assoc. Prof., UCLA, 1977-78
Visiting Investigator, Sloan-Kettering Inst., N.Y.
Visiting Prof.: UC at San Francisco; Rockefeller Univ., 1982-83, 1989-90

Memberships and Fellowships:
Amer. Assn. of Immunologists; Isr. Immunology Soc.
Resident, Soc. of the Sigma Xi, Cit Chapter.
Eur. Soc. for Cancer Research
Eur. Reticuloendothelial Soc.

Research Interests:
Functions of activated macrophages: production of TNF-alpha, IL-1 and IL-6 and the generation of nitric oxide and oxygen radicals. Modulation of macrophage functions by various agents. Cytokine production by glial cells and brain tissues. Induction and suppression of apoptosis. Effect of cannabis, cannabis derived compounds, and synthetic cannabinoids on various immune-trlated paramaters

Research Projects:
Mycoplasma fermentans induces TNF-alpha and IL-1 production by human Production of TNF-alpha by cultured astrocytes following stimulation 
Closed head injury triggers production of TNF-alpha and IL-6 by brain
Cannabinol-dexanabinal (HU-211) as a novel TNF-alpha inhibitor and Induction of apoptosis by TNF-alpha and X-irradiation and its Activation of macrophages:
Macrophage paralysis
Interaction of macrophages with embryonic cells
Interaction of macrophages with transformed T cells

Selected Publications:
Cannabidiol arrests onset of autoimmune diabetes in NOD mice 2008
Incensole acetate, a novel anti-inflammatory compound isolated 2007
Cannabidiol, a nonpsychoactive Cannabis constituent, protects2007
Potent anti-inflammatory activity of 3-aminovinylphosphonates as2007
A cannabinoid quinone inhibits angiogenesis by targeting 2006
Cannabidiol lowers incidence of diabetes in non-obese diabetic 2006
N-arachidonoyl L-serine, an endocannabinoid-like brain 2006
N-Arachidonoyl L-serine, a novel endocannabinoid-like brain 2006
New cannabidiol derivatives: Synthesis, binding to cannabinoid 2006
Cannabidiol-transdermal delivery and anti-inflammatory effect in 2003
Gamma-irradiation enhances apoptosis induced by cannabidiol, 2003
Cannabidiol: An overview of some pharmacological aspects . 2002
Inhibition of nitric oxide production for down-regulation of CNS 2001
Antioxidants attenuate acute toxicity of tumor necrosis1999
The role of brain cytokines in mediating the behavioral and1999
Glial cells production of inflammatory mediators induced by1998
Characterization of the effect of mycoplasma fermentans on the1997
Intracerebral administration of Mycoplasma fermentans in rats1997
Protection against septic shock and suppression of TNF 1997
Cytokine production in brain following closed head injury 1997
Inhibition of tumor necosis factor-alpha activity in rat brain1996
Mycoplasma stimulates the production of oxidative radicals by1995